Champions League: Man United face Inter Milan
Champions League: Man United face Inter Milan
Manchester United are the defending European champions.

New Delhi: The Champions League last 16 stage kicks into action on Tuesday night.

In Italy, Inter Milan take on Manchester United with both Jose Mourinho and Sir Alex Ferguson expecting nothing less than victory in a high octane clash.

Manchester United are the defending European champions, but Inter's confidence should be high after Saturday's 2-1 win over Bologna.

United are without the suspended Nemanja Vidic, while centre back Jonny Evans continues to struggle with an ankle injury.

The game brings Mourinho face to face with Ferguson for the first time since he left Chelsea in 2007, after sweeping the title away from United in 2005 and 2006.

Interestingly, Mourinho has only lost one of his 12 head-to-head duels with Ferguson..

"I am not saying they are afraid of us. No! In the same way I don't like these words, I know Sir Alex doesn't like the words. And I know a team like Manchester United doesn't like the words. So, I'm not saying they are afraid of us, but I am saying they respect us," said Mourinho.

Manchester United coach Sir Alex Ferguson said that his can win the match if it scores first.

"If we score I think we'll have a great chance. But you know I think it's two difficult ties. You can't split the sides at this moment in time. A team that's won the Serie A three times in a row and are going to win it again four times in a row. The experience they have. A really outstanding manager, some terrific footballers," said Ferguson.

Meanwhile, in another match Arsenal face AS Roma and after three consecutive draws in the English Premier League, Arsene Wenger would be hoping for a change in fortunes for his team.

Wenger looks likely to pair Nicklas Bendtner and Robin van Persie up front in the game as his injury-ravaged squad has left him short of options in midfield.

To make matters worse, new signing Andrei Arshavin is ineligible after playing for Zenit St Petersburg earlier in the competition.

The other big club in action is Barcelona who take on Lyon at Gerland Stadium, in Lyon.

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